Snapshot molecular imaging using coded energy-sensitive detection
Snapshot molecular imaging using coded energy-sensitive detection
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DOI：
10.1364/oe.21.025480
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发表时间：
2013-10-21
期刊：
影响因子：
3.8
通讯作者：
Brady, David
中科院分区：
文献类型：
--
作者：
Greenberg, Joel A.;Krishnamurthy, Kalyani;Brady, David
我们演示了一种从单个快照测量不同对象的距离分辨相干散射形状因子的技术。通过用x射线铅笔光束照射物体，并在能量敏感探测器元件的线性阵列前放置一个编码孔径，我们记录了相干散射的x射线。该方法的横向、范围和动量传递分辨率分别为1mm、5mm和0.2 nm(-1)，足以区分各种固体和液体。这些结果表明，在各种应用中，包括医疗诊断、质量检查和安全检测，实时体积分子成像是非破坏性检查的途径。(C) 2013年美国光学学会
We demonstrate a technique for measuring the range-resolved coherent scatter form factors of different objects from a single snapshot. By illuminating the object with an x-ray pencil beam and placing a coded aperture in front of a linear array of energy-sensitive detector elements, we record the coherently scattered x-rays. This approach yields lateral, range, and momentum transfer resolutions of 1 mm, 5 mm, and 0.2 nm(-1), respectively, which is sufficient for the distinguishing a variety of solids and liquids. These results indicate a path toward real-time volumetric molecular imaging for non-destructive examination in a variety of applications, including medical diagnostics, quality inspection, and security detection. (C) 2013 Optical Society of America