The natural history of geographic atrophy, the advanced atrophic form of age-related macular degeneration.
The natural history of geographic atrophy, the advanced atrophic form of age-related macular degeneration.
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作者：
J. Sunness
地图状萎缩是萎缩性年龄相关性黄斑变性的晚期形式。它存在于美国75岁及以上人群的3.5%。随着时间的推移，它逐渐进展，通常保留中央凹，直到疾病的后期。在基线视力良好的地图样萎缩患者中，40%至50%的患者在2年内视力下降3行或3行以上，27%的患者在4年内视力下降至20/200以下。本文讨论了目前已知的信息与年龄有关的地图状萎缩。
Geographic atrophy is the advanced form of atrophic age-related macular degeneration. It is present in 3.5% of people age 75 and over in the United States. It progresses gradually over time, often sparing the fovea until late in the course of the disease. Forty to fifty percent of eyes with geographic atrophy and good visual acuity at baseline lose three or more lines of acuity by two years and 27% become worse than 20/200 by four years. This article discusses the information known about age-related geographic atrophy at the present time.