SES1 positively regulates heat stress resistance in Arabidopsis
SES1 positively regulates heat stress resistance in Arabidopsis
复制标题
SES1 正向调节拟南芥的热应激抗性
DOI：
10.1016/j.bbrc.2019.04.015
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发表时间：
2019-06-04
影响因子：
3.1
通讯作者：
Huang, Jinguang
中科院分区：
文献类型：
--
作者：
Guan, Peiyan;Wang, Jun;Huang, Jinguang
热胁迫显著干扰植物蛋白质的折叠和加工能力。分子伴侣在未折叠/错误折叠蛋白质组装和非生物胁迫耐受中起重要作用。在这里，我们报告了SES 1，它编码一个内质网（ER）定位的分子伴侣，是所需的拟南芥耐热性。热处理对SES 1有明显的诱导作用，突变体对热胁迫敏感。热胁迫后ses 1未折叠蛋白反应基因表达上调，胞浆蛋白反应基因表达下调。此外，ER应激传感器碱性亮氨酸拉链28（bZIP 28）通过结合到SES 1的启动子区而充当SES 1的上游转录激活因子。这些结果为热应激反应和内质网应激提供了新的见解，并阐明了SES 1调节耐热性的机制。(C)2019爱思唯尔公司All rights reserved.
Heat stress significantly disturbs the protein folding and processing capability in plants. Molecular chaperones are vital players in unfolded/misfolded protein assembly and abiotic stress tolerance. Here, we reported SES1, which encodes an endoplasmic reticulum (ER) localized molecular chaperone, is required for Arabidopsis heat tolerance. SES1 is obviously induced by heat treatment and ses1 mutants are hypersensitive to heat stress. The unfolded protein response genes were up-regulated, while cytosolic protein response genes were down-regulated in ses1 after heat stress. Furthermore, ER stress sensor basic leucine zipper 28 (bZIP28) acts as the upstream transcriptional activator of SES1 by binding to its promoter region. These results provide new insights into heat stress responses and ER stress, and shed lights on the mechanism of SES1 in modulating heat resistance. (C) 2019 Elsevier Inc. All rights reserved.