In vivo MR tractography of thigh muscles using diffusion imaging: initial results
In vivo MR tractography of thigh muscles using diffusion imaging: initial results
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DOI：
10.1007/s00330-007-0713-z
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发表时间：
2007-12-01
影响因子：
5.9
通讯作者：
Cotten, A.
中科院分区：
文献类型：
--
作者：
Budzik, J. F.;Le Thuc, V.;Cotten, A.
该初步研究的目的是（1）证明在1.5T磁体上使用纤维束成像提供人体大腿肌肉的体内3D结构的可行性，以及（2）评估纤维束成像图像的价值以获得平均微结构参数，即，各向异性分数（FA）和平均表观扩散系数（ADC）。本研究纳入了5名健康志愿者。使用扩散张量成像和梯度回波T2* 序列对他们的右大腿进行成像。对每块肌肉进行了肌肉纤维束成像。磁共振纤维束成像提供了一个很好的方法，肌肉的形状和肌纤维的方向。在颜色编码方案和分配给每根纤维的光度中没有畸变。相比之下，在研究的任何肌肉中都没有绘制肌腱。FA值范围为0.27 - 0.38。平均ADC值范围为0.76至0.96 x 10 - 3 mm 2/s。我们的研究证明了在1.5T磁体上使用纤维束成像提供人体大腿肌肉的体内3D结构的可行性，并确定肌肉的微观结构参数（FA和ADC）。肌肉骨骼放射科医生应该意识到这些新的发展，可能会提供补充信息的肌肉，以通常的序列。
The aims of this preliminary study were (1) to demonstrate the feasibility of providing in vivo 3D architecture of human thigh muscles using tractography on a 1.5T magnet, and (2) to assess the value of tractography images to obtain averaged microstructural parameters, i.e., the fractional anisotropy (FA) and the mean apparent diffusion coefficient (ADC), over the whole thigh. Five healthy volunteers were included in this study. Their right thighs were imaged using diffusion tensor imaging and gradient-echo T2* sequences. Muscular tractography was performed on each muscle. MR tractography provided a good approach of the muscle shape and of the orientation of the muscle fibers. There was no aberration in the color-encoding scheme nor in the luminosity assigned to each fiber. In contrast, tendons were not drawn in any of the muscles studied. FA values ranged from 0.27 to 0.38. Mean ADC values ranged from 0.76 to 0.96 x 10(-3) mm(2)/s. Our study demonstrated the feasibility of providing in vivo 3D architecture of human thigh muscles using tractography on a 1.5T magnet, and of determining muscular microstructural parameters (FA and ADC). Musculoskeletal radiologists should be aware of these new developments that may provide complementary information on muscles to the usual sequences.