A Nationwide Survey of the Extent of Autopsy in Sudden Unexplained Death in Epilepsy
A Nationwide Survey of the Extent of Autopsy in Sudden Unexplained Death in Epilepsy
复制标题
全国范围内癫痫不明原因猝死尸检范围调查
DOI：
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发表时间：
2009
影响因子：
1
通讯作者：
E. So
中科院分区：
文献类型：
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作者：
P. Schraeder;Kristen Delin;R. McClelland;E. So
癫痫猝死是一种灾难性事件，需要尸检才能确诊。在验尸官和病理学家中，缺乏对癫痫猝死的认识，这是癫痫死亡的一个重要原因。本调查研究的美国验尸官和法医（MEs）评估他们的尸检患者癫痫谁突然死亡没有明显原因。对510份调查回复的分析表明，病理学家比非病理学家更倾向于常规询问心脏病史，切除大脑进行检查，或采集血液样本以确定抗惊厥药和精神药物。城市验尸官和法医比非城市的同事更有可能取出大脑进行检查或收集血液样本进行这些确定。缺乏家属同意和尸检费用是不对癫痫患者进行尸检的主要原因。我们的研究强调了向所有验尸官和医学助理以及公众宣传在死亡原因不明显的情况下对癫痫患者进行彻底尸检的重要性。
Sudden unexplained death in epilepsy is a catastrophic event that requires autopsy for definitive diagnosis. Lack of awareness of sudden unexplained death in epilepsy as an important cause of death in epilepsy has been observed among coroners and pathologists. This survey study of US coroners and medical examiners (MEs) assesses their postmortem examinations of persons with epilepsy who had died suddenly without obvious cause. Analysis of the 510 survey responses shows that pathologists are significantly more likely than nonpathologists to inquire routinely about a history of cardiac disease, remove the brain for examination, or collect blood samples for determinations of anticonvulsant and psychotropic drugs. Urban coroners and MEs are significantly more likely than their nonurban colleagues to remove the brain for examination or collect blood samples for these determinations. Lack of family consent and the cost of autopsy are major reasons for not performing an autopsy of persons with epilepsy. Our study underscores the importance of promoting to all coroners and MEs and to the public the need for thorough autopsy of persons with epilepsy when the cause of death is not obvious.