Multiparametric magnetic resonance imaging for the differentiation of low and high grade clear cell renal carcinoma

Multiparametric magnetic resonance imaging for the differentiation of low and high grade clear cell renal carcinoma
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DOI:
10.1007/s00330-014-3380-x
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发表时间:
2015-01-01
期刊:
影响因子:
5.9
通讯作者:
Grenier, N.
Grenier, N.
中科院分区:
医学2区
文献类型:
--
作者:
Cornelis, F.;Tricaud, E.;Grenier, N.

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目的回顾性分析80例经病理证实的肾细胞癌(透明细胞癌57例,乳头状癌16例,嫌色细胞癌7例)的MRI表现,评价MRI对低、高Fuhrman分级肾细胞癌的鉴别诊断价值。双回波化学位移,动态对比增强T1和T2加权图像和表观扩散系数(ADC)地图进行了独立审查。计算肿瘤信号强度指数(SII)、肿瘤与脾脏信号强度比值(TSR)、ADC值、洗入指数(WiI)和洗出指数(WoI),并与病理分级和大小进行比较。采用Fuhrman评分系统。低等级(评分
Purpose To retrospectively evaluate the ability of magnetic resonance (MR) imaging to differentiate low from high Fuhrman grade renal cell carcinoma (RCC).Materials and methods MR images from 80 consecutive pathologically proven RCC (57 clear cell, 16 papillary and 7 chromophobe) were evaluated. Double-echo chemical shift, dynamic contrast-enhanced T1- and T2-weighted images and apparent diffusion coefficient (ADC) maps were reviewed independently. Signal intensity index (SII), tumour-to-spleen SI ratio (TSR), ADC ratio, wash-in (WiI) and wash-out indices (WoI) between different phases were calculated and compared to pathological grade and size. The Fuhrman scoring system was used. Low grade (score