AN EVALUATION OF INTERNAL-MAMMARY-ARTERY LIGATION BY A DOUBLE-BLIND TECHNIC
AN EVALUATION OF INTERNAL-MAMMARY-ARTERY LIGATION BY A DOUBLE-BLIND TECHNIC
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DOI：
10.1056/nejm195905282602204
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发表时间：
1959-01-01
影响因子：
158.5
通讯作者：
BRUCE, RA
中科院分区：
文献类型：
--
作者：
COBB, LA;THOMAS, GI;BRUCE, RA
采用双盲法观察了乳内动脉结扎术治疗心绞痛17例的疗效。在前6个月，结扎组8名患者中有5名和未结扎组9名患者中有5名报告了“显著”的主观改善。2例未结扎乳内动脉的患者运动耐量显著改善，其中1例患者在相同的运动试验中未能显示术前发生的异常心电图变化。乳内动脉结扎可能对冠状动脉疾病的病理生理没有影响。
Effects of internal-mammary-artery ligation on 17 patients with angina pectoris were evaluated by a double-blind technic. During the first 6 months, 5 out of 8 of the ligated patients and 5 out of 9 of the nonligated reported "significant" subjective improvement. Striking improvement in exercise tolerance occurred in 2 patients whose internal mammary arteries were not ligated; 1 of these patients failed to demonstrate the abnormal ecg changes that occurred preoperatively with the same exercise test. Internal-mammary-artery ligation probably has no effect on the pathophysiology of coronary-artery disease.