Chemical cues are necessary but insufficient for reproductive activation of female pine vole (Microtus pinetorum).
Chemical cues are necessary but insufficient for reproductive activation of female pine vole (Microtus pinetorum).
复制标题
化学信号对于雌性松田鼠（Microtus pinetorum）的生殖激活是必要的，但还不够。
DOI：
10.1095/biolreprod54.5.1038
复制
发表时间：
1996
影响因子：
3.6
通讯作者：
Barghusen,L
中科院分区：
文献类型：
--
作者：
Solomon,NG;Vandenbergh,JG;Wekesa,KS;Barghusen,L
在各种Arvicoline啮齿动物中，繁殖受到不同程度的社会因素的影响，包括行为或化学线索。由于先前的研究表明，来自成年雄性的化学信号可以繁殖地激活雌性松鼠(Microtus Pinetorum)，我们试图具体确定哪种类型的刺激促进激活反应。在这些实验中，雌性被暴露在陌生的成年雄性面前，或受到雄性暗示的某种组合，或被单独安置。使用子宫质量作为生殖活动的衡量标准，我们发现，无论是暴露在男性尿液中还是暴露在男性污染的床上用品中，女性都不会被激活，但与男性完全接触显然会导致子宫更重。接受手术切除犁鼻器官的雌性在与雄性一起居住时，无法进行生殖激活。最后，与只允许接触来自雄性的化学物质的雌性相比，雌性直接住在雄性下面的雌性子宫更重。在雌性Arvicoline啮齿动物中，似乎在绝对依赖雄性接触和化学线索与绝对独立于生殖激活之间存在着生理上的连续体。目前的结果使雌性松鼠更接近前者的极端，而不是后者。
Among various arvicoline rodents, reproduction is influenced to varying degrees by social factors, including behavioral or chemical cues. Since previous research suggested that chemosignals from adult males reproductively activate female pine voles (Microtus pinetorum), we sought to determine specifically what types of stimuli promote the activation response. In these experiments, female were exposed to unfamiliar adult males, or to some combination of cues from males, or were housed alone. Using uterine mass as a measure of reproductive activation, we found that females were not activated by exposure either to male urine by itself or to male-soiled bedding by itself, but full contact with a male clearly resulted in heavier uteri. Females whose vomeronasal organs were surgically excised failed to undergo reproductive activation when housed with males. Finally, females allowed physical contact by being housed directly underneath males had heavier uteri than did females whose housing allowed contact only with the chemical cues from males. Among female arvicoline rodents, it appears that there exists a physiological continuum between absolute dependence on both contact and chemical cues from males vs. absolute independence for reproductive activation. The present results place female pine voles closer to the former extreme than to the latter.