Syngeneic sensitization of mouse lymphocytes on monolayers of thyroid epithelial cells. VI. Evaluation of its frequency using the limiting dilution analysis.
Syngeneic sensitization of mouse lymphocytes on monolayers of thyroid epithelial cells. VI. Evaluation of its frequency using the limiting dilution analysis.
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小鼠淋巴细胞对单层甲状腺上皮细胞的同基因致敏。
DOI：
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发表时间：
2008
期刊：
影响因子：
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通讯作者：
J. Salamero
中科院分区：
文献类型：
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作者：
J. Charreire;J. Salamero
采用有限稀释法测定正常脾细胞参与甲状腺上皮细胞（TEC）原发性同基因致敏（PSS）的频率。结果发现，它们的频率，达到1：5440，与主要组织相容性复合体（MHC）抗原（K端或D端）和暴露在TEC单层表面的特异性抗原甲状腺球蛋白（Tg）的表达有关。此外，通过加入25%的正常同系淋巴结（LN）细胞，该频率显著降低。
The determination of the frequency of normal spleen cell involvement in Primary syngeneic sensitization (PSS) against thyroid epithelial cells (TEC) was performed using the limiting dilution analysis. It was found that their frequency, which reaches 1:5440, is related to the expression of major histocompatibility complex (MHC) antigens (K end or D end) and of the specific antigen thyroglobulin (Tg) exposed on the surface of the TEC monolayer. Moreover, a significant diminution of this frequency was obtained by the addition of 25% normal syngeneic lymph node (LN) cells.
T 细胞的存在表现出与同种异体反应性无法区分的自身反应性。
DOI：
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发表时间：
1980
期刊：
Journal of immunology (Baltimore, Md. : 1950)
影响因子：
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作者：
Altman,A;Katz,DH
通讯作者：
Katz,DH