Presence of Helicobacter pylori in patients with non-ulcer dyspepsia revealing normal antral histological characteristics.

Presence of Helicobacter pylori in patients with non-ulcer dyspepsia revealing normal antral histological characteristics.
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非溃疡性消化不良患者中幽门螺杆菌的存在揭示了正常的胃窦组织学特征。

DOI:
10.1159/000200473
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发表时间:
1990
期刊:
影响因子:
3.2
通讯作者:
J. Arends
J. Arends
中科院分区:
医学3区
文献类型:
--
作者:
R. Loffeld;E. Stobberingh;J. Flendrig;J. Arends

文献摘要

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对连续200例非溃疡性消化不良患者胃窦炎和正常胃窦黏膜幽门螺杆菌进行了研究,采用培养、改良吉姆萨染色和敏感免疫过氧化物酶染色联合检测。幽门螺杆菌胃炎发生率为56%。75%的正常胃窦粘膜病例中存在这种细菌,但数量较少。结果表明,87%的非溃疡性消化不良患者为polory阳性,这意味着微生物的作用比最初认为的更大。
Two hundred consecutive patients suffering from non-ulcer dyspepsia were studied for the presence of Helicobacter pylori in antral gastritis and normal antral mucosa, using the combination of culture, modified Giemsa stain and a sensitive immunoperoxidase stain as means of detection. H. pylori gastritis was present in 56% of the cases. The bacterium was present in 75% of cases of normal antral mucosa, however, in low numbers. It is concluded that 87% of patients with non-ulcer dyspepsia are H. polory-positive implying a larger role for the micro-organism as initially thought.