Multiregional Tumor Trees Are Not Phylogenies.
Multiregional Tumor Trees Are Not Phylogenies.
复制标题
DOI:
10.1016/j.trecan.2017.06.004
复制
发表时间:
2017-08
期刊:
影响因子:
18.4
通讯作者:
Posada D
中科院分区:
文献类型:
--
作者:
Alves JM;Prieto T;Posada D
Tumor samples most often comprise a mixture of different cell lineages. Multiregional trees built from bulk mutational profiles do not consider this heterogeneity and can potentially lead to erroneous evolutionary inferences, including biased timing of somatic mutations, spurious parallel mutation events, and/or incorrect chronological ordering of metastatic events.
登录
查看更多内容
影响因子:
82.9
作者:
Andor N;Graham TA;Jansen M;Xia LC;Aktipis CA;Petritsch C;Ji HP;Maley CC
通讯作者:
Maley CC
影响因子:
6.5
作者:
Maddison, WP
通讯作者:
Maddison, WP
影响因子:
16.6
作者:
Zhai W;Lim TK;Zhang T;Phang ST;Tiang Z;Guan P;Ng MH;Lim JQ;Yao F;Li Z;Ng PY;Yan J;Goh BK;Chung AY;Choo SP;Khor CC;Soon WW;Sung KW;Foo RS;Chow PK
通讯作者:
Chow PK
DOI:
10.1056/nejmoa1113205
发表时间:
2012-03-08
期刊:
The New England journal of medicine
影响因子:
--
作者:
Gerlinger M;Rowan AJ;Horswell S;Math M;Larkin J;Endesfelder D;Gronroos E;Martinez P;Matthews N;Stewart A;Tarpey P;Varela I;Phillimore B;Begum S;McDonald NQ;Butler A;Jones D;Raine K;Latimer C;Santos CR;Nohadani M;Eklund AC;Spencer-Dene B;Clark G;Pickering L;Stamp G;Gore M;Szallasi Z;Downward J;Futreal PA;Swanton C
通讯作者:
Swanton C
影响因子:
82.9
作者:
Yates LR;Gerstung M;Knappskog S;Desmedt C;Gundem G;Van Loo P;Aas T;Alexandrov LB;Larsimont D;Davies H;Li Y;Ju YS;Ramakrishna M;Haugland HK;Lilleng PK;Nik-Zainal S;McLaren S;Butler A;Martin S;Glodzik D;Menzies A;Raine K;Hinton J;Jones D;Mudie LJ;Jiang B;Vincent D;Greene-Colozzi A;Adnet PY;Fatima A;Maetens M;Ignatiadis M;Stratton MR;Sotiriou C;Richardson AL;Lønning PE;Wedge DC;Campbell PJ
通讯作者:
Campbell PJ