Cytogenetic testing of anembryonic pregnancies compared to embryonic missed abortions
Cytogenetic testing of anembryonic pregnancies compared to embryonic missed abortions
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DOI：
10.1007/s10815-007-9166-1
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发表时间：
2007-11-01
影响因子：
3.1
通讯作者：
Milki, Amin A.
中科院分区：
文献类型：
--
作者：
Lathi, Ruth B.;Mark, Sara D.;Milki, Amin A.
目的-本研究的目的是要确定的异常率检测的细胞遗传学检测的头三个月流产，在患者和没有胚胎极上看到ultrason.Materials和方法的一项回顾性研究，272 D&Cs的过期流产在学术不孕不育的做法，从1999年至2006年。核型结果与经阴道超声检查结果进行比较。卡方分析与P0.05）。结论在两组中检测到的异常率高，这表明，有用的结果可以从POC的染色体检测，无论超声结果。需要进一步研究染色体检测的预后价值和成本效益。
Purpose The objective of this study is to determine the rate of abnormalities detected by cytogenetic testing of first trimester miscarriages, in patients with and without an embryonic pole seen on ultrasound.Materials and methods A retrospective study of 272 D&Cs for missed abortions in an academic infertility practice from 1999 to 2006. Karyotype results were compared with transvaginal ultrasound findings. Chi-squared analysis was used with a P0.05).Conclustion The high rate of abnormalities detected in both groups suggests that useful results can be obtained from chromosomal testing of the POC regardless of ultrasound findings. Further studies on the prognostic value and cost effectiveness of chromosomal testing are needed.