In(III)-catalyzed tandem reaction of chromone-derived Morita-Baylis-Hillman alcohols with amines.
In(III)-catalyzed tandem reaction of chromone-derived Morita-Baylis-Hillman alcohols with amines.
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DOI：
10.1039/c0ob00604a
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发表时间：
2011-01
影响因子：
3.2
通讯作者：
Chen Wu;Yu-Liang Liu;Hao Zeng;Li Liu;Dong Wang;Yong-Jun Chen
中科院分区：
文献类型：
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作者：
Chen Wu;Yu-Liang Liu;Hao Zeng;Li Liu;Dong Wang;Yong-Jun Chen
以In(OTf)(3)为催化剂，一锅法合成2-取代-3-氨基亚甲基杂环胺。该方案包括串联的烯丙胺化/色曼开环/Michael环化反应。
The reaction of chromone-derived cyclic Morita-Baylis-Hillman alcohols with amines catalyzed by In(OTf)(3) in a one pot process was developed for the convenient and efficient synthesis of 2-substituted-3-aminomethylenechromans. The tandem allylic amination/chromen ring-opening/Michael cyclization reactions were involved in this protocol.