Hyperacute stroke: Evaluation with combined multisection diffusion-weighted and hemodynamically weighted echo-planar MR imaging

Hyperacute stroke: Evaluation with combined multisection diffusion-weighted and hemodynamically weighted echo-planar MR imaging
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DOI:
10.1148/radiology.199.2.8668784
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发表时间:
1996-05-01
期刊:
影响因子:
19.7
通讯作者:
Koroshetz, WJ
Koroshetz, WJ
中科院分区:
医学1区
文献类型:
--
作者:
Sorensen, AG;Buonanno, FS;Koroshetz, WJ

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目的:应用常规、多层弥散加权(DW)和血流动力学加权(HW)磁共振成像评价急性脑卒中。材料和方法:对11例急性偏瘫患者在发病后10h内进行三种磁共振成像检查。结果:11例患者中有9例在DW和HW成像上发现异常,而在首次CT和/或MR发现正常的情况下,所有9例患者在随访CT或MR时均可显示梗塞,DW异常一般较小,HW异常一般大于随后成像所确定的梗塞体积。2例DW和HW成像正常的患者,症状在1-48小时内完全消失。结论:在常规MR或CT显示脑梗塞之前,DW和HW成像可显示超急性期脑缺血的不同方面。这些技术可能会改善中风的诊断,并可能有助于治疗的进步。
PURPOSE: To evaluate acute stroke with conventional, multisection diffusion-weighted (DW), and hemodynamically weighted (HW) magnetic resonance (MR) imaging.MATERIALS AND METHODS: The three MR imaging techniques were performed in 11 patients within 10 hours of the onset of acute hemiparesis. The volume of DW and HW abnormalities were compared with infarct volumes depicted at initial and/or follow-up MR or computed tomography (CT).RESULTS: Findings at DW and HW imaging were abnormal in nine of the 11 patients, despite normal findings at initial CT and/or MR. In all nine patients, infarcts were depicted at follow-up CT or MR. The DW abnormality was generally smaller and the HW abnormality was generally larger than the infarct volume determined at subsequent imaging. In the two patients with normal findings at DW and HW imaging, symptoms resolved completely within 1-48 hours.CONCLUSION: Different aspects of hyperacute cerebral ischemia are depicted at DW and HW imaging before infarction is depicted at conventional MR or CT. These techniques may improve stroke diagnosis and may contribute to advances in treatment.