Prenatal DHA supplementation and infant attention

Prenatal DHA supplementation and infant attention
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DOI:
10.1038/pr.2016.134
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发表时间:
2016-11-01
期刊:
影响因子:
3.6
通讯作者:
Carlson, Susan E.
Carlson, Susan E.
中科院分区:
医学3区
文献类型:
--
作者:
Colombo, John;Gustafson, Kathleen M.;Carlson, Susan E.

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背景技术背景:产前二十二碳六烯酸(DHA)对婴儿认知的影响随机试验的结果是混合的,但大多数试验都使用全球标准化的结果,这可能是不敏感的DHA对特定的认知domains.METHODS的影响:妇女被随机分配到600毫克/天的DHA或安慰剂的最后两个孕期。这些母亲的婴儿,然后在4,6,9个月的年龄测试的视觉habituation。结果:DHA补充剂并没有影响外观持续时间或习惯化参数,但婴儿补充母亲保持高水平的持续关注(SA)在第一年,SA下降安慰剂组。补充组也表现出显着减少磨损的习惯性任务,特别是在6和9个月。结论:研究结果支持的建议,产前DHA可能会积极影响婴儿的注意力和调节状态。
BACKGROUND: Results of randomized trials on the effects of prenatal docosahexaenoic acid (DHA) on infant cognition are mixed, but most trials have used global standardized outcomes, which may not be sensitive to effects of DHA on specific cognitive domains.METHODS: Women were randomized to 600 mg/d DHA or a placebo for the last two trimesters of pregnancy. Infants of these mothers were then followed on tests of visual habituation at 4, 6, and 9 mo of age.RESULTS: DHA supplementation did not affect look duration or habituation parameters but infants of supplemented mothers maintained high levels of sustained attention (SA) across the first year; SA declined for the placebo group. The supplemented group also showed significantly reduced attrition on habituation tasks, especially at 6 and 9 mo.CONCLUSION:The findings support with the suggestion that prenatal DHA may positively affect infants' attention and regulation of state.