The effect of temperature on systolic blood pressure
The effect of temperature on systolic blood pressure
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DOI：
10.1097/mbp.0b013e3280b083f4
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发表时间：
2007-06-01
影响因子：
1.3
通讯作者：
Dobson, Annette J.
中科院分区：
文献类型：
--
作者：
Barnett, Adrian G.;Sans, Susana;Dobson, Annette J.
目的量化收缩压与季节、室内外温度及室外温度短期变化趋势的关系。方法采用世卫组织MONICA项目风险因素调查数据，调查对象为16个国家的25个人群。随机抽取年龄在35-64岁之间的男性和女性样本参与研究。对115434名参与者进行了收缩压测量。分层模型被用来量化血压和体温之间的关系，并解释不同人群之间关系的差异。结果靠近赤道的人群血压的季节性变化较大。室内温度每升高1℃，收缩压平均降低0.31 mmHg（95%后验间隔：-0.44,-0.19）。室外温度升高1℃，血压平均降低0.19 mmHg（95%后验区间：-0.26,-0.11）。室外（而非室内）温度升高对女性的影响比男性更大。控制室内温度后，室外温度的影响仍然存在。气温的短期趋势在统计上没有显著的影响。结论室内和室外温度对收缩压有独立的影响，在测量血压的研究中应控制两者。改善对寒冷温度的保护可以减少冬季心血管疾病的死亡率。
Objectives To quantify the association between systolic blood pressure and season, indoor and outdoor temperature and short-term trends in outdoor temperature.Methods The study used data from the WHO MONICA Project risk factors surveys from 25 populations in 16 countries. Random samples of men and women aged 35-64 years were invited to participate. Systolic blood pressure measurements were available for 115434 participants. Hierarchical models were used to quantify the association between blood pressure and temperature, and account for differences in the associations between populations.Results Populations closer to the equator showed larger seasonal changes in blood pressure. A 1 degrees C increase in indoor temperature reduced systolic blood pressure by an average of 0.31 mmHg (95% posterior interval: -0.44, -0.19). A 1 degrees C increase in outdoor temperature reduced blood pressure by the smaller average of 0.19 mmHg (95% posterior interval: -0.26, -0.11). Increased outdoor, but not indoor, temperatures had a stronger effect in women than in men. The effect of outdoor temperature remained after controlling for indoor temperature. Short-term trends in temperature did not have a statistically significant effect.Conclusions Indoor and outdoor temperature have independent effects on systolic blood pressure, and both should be controlled for in studies that measure blood pressure. Improved protection against cold temperatures could lead to a reduction in the winter excess of cardiovascular mortality.