Beta-binders for Biological Quantitative Experiments
Beta-binders for Biological Quantitative Experiments
复制标题
用于生物定量实验的β-结合剂
DOI：
10.1016/j.entcs.2006.07.014
复制
发表时间：
2006
影响因子：
6.8
通讯作者：
P. Quaglia
中科院分区：
文献类型：
--
作者：
P. Degano;D. Prandi;C. Priami;P. Quaglia
生物系统与分布式和移动的系统之间的相似性表明，过程演算理论可能是理解（如果不是预测）复杂生物系统行为的有用起点。为了正式模拟体外或体内实验，必须研究过程结石的适当定量扩展。本文重点介绍了β-结合剂，一种语言的进程与类型的相互作用网站，最近推出的准确地表示生物实体。在这里，β-结合物的语法和语义被丰富，以实现它的随机版本，以获得对生物现象的定量测量。定量参数来自于引入亲和力概念的类型化相互作用位点。定量推理的相关性概述运行一个生物学的例子。
The similarities between biological systems and distributed and mobile systems suggest that the theory of process calculi could be a useful starting point for understanding, if not predicting, the behaviour of complex biological systems. To formally model in vitro or in vivo experiments, appropriate quantitative extensions of process calculi have to be investigated. This paper focuses on Beta-binders, a language of processes with typed interaction sites which has been recently introduced to accurately represent biological entities. Here the syntax and semantics of Beta-binders are enriched to achieve a stochastic version of it, in order to obtain quantitative measures on biological phenomena. The quantitative parameters are derived from typed interaction sites introducing the concept of affinity. The relevance of quantitative reasoning is outlined running a biological example.
影响因子：
5.6
作者：
KUNTZ, ID;BLANEY, JM;FERRIN, TE
通讯作者：
FERRIN, TE