Coregistration of digital photography of the human cortex and cranial magnetic resonance imaging for visualization of subdural electrodes in epilepsy surgery
Coregistration of digital photography of the human cortex and cranial magnetic resonance imaging for visualization of subdural electrodes in epilepsy surgery
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DOI：
10.1227/01.neu.0000303992.87987.17
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发表时间：
2007-11-01
期刊：
影响因子：
4.8
通讯作者：
Schaller, Karl
中科院分区：
文献类型：
--
作者：
Mahvash, Mehran;Koenig, Roy;Schaller, Karl
目的：为了开发一种方法，为cocregistration的数字照片的人类大脑皮层与头部磁共振成像（MRI）扫描侵入性诊断和切除新皮质癫痫surgery.METHODS：6例慢性癫痫患者（2名女性，4名男性;平均年龄，34岁;年龄范围，20-43岁）进行术前三维（3D）TI加权MRI扫描。在植入硬膜下网格电极期间拍摄暴露皮质的数字照片。使用渲染软件（Analyze 3.1; Biomedical Imaging Resource，马约基金会，罗切斯特，MN）创建脑表面的基于MRI的3D模型。使用Analyze软件中的配准工具将数字照片与脑表面MRI模型手动配准。通过匹配的数字照片和大脑表面模型，硬膜下电极的位置被整合到术前获得的三维MRI dataset.Results的坐标系中：在所有患者中，标记的电极接触相对于皮质解剖结构的位置可以在皮质表面的三维模型上可视化。在切除的时候，所得到的图像的配准过程提供了一个现实的视图的皮层和硬膜下electrode.CONCLUSION的位置：的大脑皮层的数字照片与3D MRI数据集的结果的配准是可能的。这允许识别硬膜下网格电极下面的解剖细节，并增强外科医生的定向。
OBJECTIVE: To develop a method for the coregistration of digital photographs of the human cortex with head magnetic resonance imaging (MRI) scans for invasive diagnostics and resective neocortical epilepsy surgery.METHODS: Six chronically epileptic patients (two women, four men; mean age, 34 yr; age range, 20-43 yr) underwent preoperative three-dimensional (3D) TI -weighted MRI scans. Digital photographs of the exposed cortex were taken during implantation of subdural grid electrodes. Rendering software (Analyze 3.1; Biomedical Imaging Resource, Mayo Foundation, Rochester, MN) was used to create an MRI-based 3D model of the brain surface. Digital photographs were manually coregistered with the brain surface MRI model using the registration tool in the Analyze software. By matching the digital photograph and the brain surface model, the position of the subdural electrodes was integrated into the coordinate system of the preoperatively acquired 3D MRI dataset.RESULTS: In all patients, the position of the labeled electrode contacts in relation to the cortical anatomy could be visualized on the 3D models of the cortical surface. At the time of resection, the resulting image of the coregistration process provides a realistic view of the cortex and the position of the subdural electrode.CONCLUSION: The coregistration of digital photographs of the brain cortex with the results of 3D MRI data sets is possible. This allows for identification of anatomic details underlying the subdural grid electrodes and enhances the orientation of the surgeon.