Virus inactivation in aluminum and polyaluminum coagulation.
Virus inactivation in aluminum and polyaluminum coagulation.
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DOI：
10.1021/es0343003
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发表时间：
2003-10
影响因子：
11.4
通讯作者：
Y. Matsui;T. Matsushita;S. Sakuma;Takahito Gojo;T. Mamiya;Hiroshi Suzuoki;Takanobu Inoue
中科院分区：
文献类型：
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作者：
Y. Matsui;T. Matsushita;S. Sakuma;Takahito Gojo;T. Mamiya;Hiroshi Suzuoki;Takanobu Inoue
无机铝盐（例如硫酸铝）是凝结剂，可导致细菌和病毒等小颗粒以及无机颗粒不稳定并结合成较大的聚集体。在本研究中，使用四种不同的铝混凝剂对掺有 Qbeta、MS2、T4 和 P1 病毒的水样进行批量混凝处理。通过用碱性牛肉提取物溶液提高pH值来溶解絮凝颗粒后，测量最终通过加入凝结剂而形成的絮凝颗粒悬浮液中的总传染性病毒浓度。在水样中加入铝混凝剂后，病毒浓度大大降低。然而，与预先形成的氢氧化铝絮体混合并吸附在其上的病毒在絮体溶解后完全恢复。这些结果表明铝凝固过程可以灭活病毒。预水解铝盐凝结剂聚合氯化铝 (PACl) 的杀病毒活性最为显着。河水中的杀病毒活性低于超纯水——河水中的天然有机物抑制了病毒活性。讨论了病毒灭活的机制和动力学。我们的结果表明，铝凝固剂水解过程中形成的中间聚合物对病毒有强烈的吸附作用，要么使它们失去活性，要么防止传染性。
Inorganic aluminum salts, such as aluminum sulfate, are coagulants that cause small particles, such as bacteria and viruses as well as inorganic particles, to destabilize and combine into larger aggregates. In this investigation, batch coagulation treatments of water samples spiked with Qbeta, MS2, T4, and P1 viruses were conducted with four different aluminum coagulants. The total infectious virus concentration in the suspension of floc particles that eventually formed by dosing with coagulant was measured after the floc particles were dissolved by raising the pH with an alkaline beef extract solution. The virus concentrations were extremely reduced after the water samples were dosed with aluminum coagulants. Viruses mixed with and adsorbed onto preformed aluminum hydroxide floc were, however, completely recovered after the floc dissolution. These results indicated that the aluminum coagulation process inactivates viruses. Virucidal activity was most prominent with the prehydrolyzed aluminum salt coagulant, polyaluminum chloride (PACl). Virucidal activity was lower in river water than in ultrapure water--natural organic matter in the river water depressed the virucidal activity. Mechanisms and kinetics of the virus inactivation were discussed. Our results suggest that intermediate polymers formed during hydrolysis of the aluminum coagulants sorbed strongly to viruses, either rendering them inactive or preventing infectivity.