Total cholesterol and risk of mortality in the oldest old
Total cholesterol and risk of mortality in the oldest old
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DOI：
10.1016/s0140-6736(97)04430-9
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发表时间：
1997-10-18
期刊：
影响因子：
168.9
通讯作者：
Westendorp, RGJ
中科院分区：
文献类型：
--
作者：
WeverlingRijnsburger, AWE;Blauw, GJ;Westendorp, RGJ
背景血清总胆固醇作为心血管疾病的危险因素，其影响随着年龄的增长而降低，这使老年人降胆固醇治疗的必要性受到质疑。我们评估了总胆固醇浓度对85岁及以上人群的特定和全因死亡率的影响。方法在724名参与者（中位年龄89岁）中，测量总胆固醇浓度，并计算10年以上的随访死亡风险。总胆固醇浓度分为三类
Background The impact of total serum cholesterol as a risk factor for cardiovascular disease decreases with age, which casts doubt on the necessity for cholesterol-lowering therapy in the elderly. We assessed the influence of total cholesterol concentrations on specific and all-cause mortality in people aged 85 years and over.Methods In 724 participants (median age 89 years), total cholesterol concentrations were measured and mortality risks calculated over 10 years of follow-up. Three categories of total cholesterol concentrations were defined