The Tromsø heart study. Does coffee raise serum cholesterol?
The Tromsø heart study. Does coffee raise serum cholesterol?
复制标题
特罗姆瑟心脏研究。咖啡会升高血清胆固醇吗？
DOI：
--
复制
发表时间：
1983
影响因子：
158.5
通讯作者：
O. Førde
中科院分区：
文献类型：
--
作者：
D. Thelle;E. Arnesen;O. Førde
我们研究了年龄在20岁至54岁之间的7213名女性和7368名男性的咖啡摄入量与血清总胆固醇、高密度脂蛋白（HDL）胆固醇和甘油三酯水平之间的关系。咖啡消费量与男女的总胆固醇和甘油三酯水平呈正相关，与女性的HDL胆固醇水平呈负相关。在调整了年龄、体重指数对数、闲暇时的体力活动、吸烟和饮酒后，咖啡与胆固醇的关系仍然很强，具有统计学显著性（协方差分析P <0.0001）。调整所有协变量后，总胆固醇水平为5.56 +/- 0.05 mmol/L（平均值+/-SE）在每天喝咖啡少于一杯的男性中，相比之下，每天喝九杯以上的人每升6.23 +/- 0.03 mmol。妇女的相应数字为每升5.32 +/- 0.05和5.92 +/- 0.04 mmol。考虑的其他变量都不能解释这种关系。我们的结论是，咖啡消费是总胆固醇水平变化的主要贡献者。
We examined the relation between coffee consumption and levels of serum total cholesterol, high-density-lipoprotein (HDL) cholesterol, and triglycerides in a population of 7213 women and 7368 men between the ages of 20 and 54 years. Coffee consumption was positively associated with levels of total cholesterol and triglycerides in both sexes and was inversely associated with levels of HDL cholesterol in women. The coffee-cholesterol relation remained strong and statistically significant (P less than 0.0001 in a covariance analysis) after adjustment for age, logarithm of body-mass index, physical activity in leisure time, cigarette smoking, and alcohol consumption. After adjustment for all covariates, the total cholesterol level was 5.56 +/- 0.05 mmol per liter (mean +/- S.E.) in men drinking less than one cup of coffee a day, as compared with 6.23 +/- 0.03 mmol per liter in those consuming more than nine cups a day. The corresponding figures for women were 5.32 +/- 0.05 and 5.92 +/- 0.04 mmol per liter. None of the other variables considered could explain this relation. We conclude that coffee consumption is a major contributor to the variation in levels of total cholesterol.