Advanced reproductive age and fertility: no. 269, November 2011.
Advanced reproductive age and fertility: no. 269, November 2011.
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发表时间：
2012
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通讯作者：
Liu Kimberly;Allison M. Case;Anthony P. Cheung;Sony Sierra;Saleh AlAsiri;B. Carranza-Mamane;Cathie Dwyer;James Graham;J. Havelock;R. Hemmings;Francis Lee;Kimberly E Liu;W. Murdock;V. Senikas;T. Vause;Benjamin Chee-Man Wong
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作者：
Liu Kimberly;Allison M. Case;Anthony P. Cheung;Sony Sierra;Saleh AlAsiri;B. Carranza-Mamane;Cathie Dwyer;James Graham;J. Havelock;R. Hemmings;Francis Lee;Kimberly E Liu;W. Murdock;V. Senikas;T. Vause;Benjamin Chee-Man Wong
目的提高对自然生育和辅助生殖技术（ART）方面女性和男性生育力自然年龄相关性下降的认识，并为其管理提供建议，并回顾评估卵巢老化的调查。本指南回顾了对患有不孕症的高龄育龄妇女使用ART评估卵巢储备和生育力治疗的选择。结果测量的结果是卵巢储备功能测试的预测价值和自然和辅助生育的妊娠率。证据2010年6月，通过检索PubMed或Medline、CINAHL和科克伦图书馆，使用适当的关键词（卵巢老化、卵巢储备、高龄产妇、高龄父亲、ART）检索已发表文献。结果仅限于系统综述、随机对照试验/对照临床试验和观察性研究。没有日期或语言限制。定期更新这些信息，并将其纳入2010年12月之前的准则。使用加拿大预防保健工作组报告中描述的标准对证据质量进行评级。根据该报告中描述的方法对实践建议进行了排名（表）。益处、危害和成本初级和专科医疗保健提供者和妇女将更好地了解卵巢衰老和与年龄相关的自然生育能力下降以及辅助生殖技术的选择。
OBJECTIVE To improve awareness of the natural age-related decline in female and male fertility with respect to natural fertility and assisted reproductive technologies (ART) and provide recommendations for their management,and to review investigations in the assessment of ovarian aging. OPTIONS This guideline reviews options for the assessment of ovarian reserve and fertility treatments using ART with women of advanced reproductive age presenting with infertility. OUTCOMES The outcomes measured are the predictive value of ovarian reserve testing and pregnancy rates with natural and assisted fertility. EVIDENCE Published literature was retrieved through searches of PubMed or Medline, CINAHL, and The Cochrane Library in June 2010, using appropriate key words (ovarian aging, ovarian reserve, advanced maternal age, advanced paternal age, ART). Results were restricted to systematic reviews, randomized controlled trials/controlled clinical trials, and observational studies. There were no date or language restrictions. Searches were updated on a regular basis and incorporated into the guideline to December 2010. VALUES The quality of evidence was rated using the criteria described in the Report of the Canadian Task Force on Preventive Health Care. Recommendations for practice were ranked according to the method described in that report (Table). BENEFITS, HARMS, AND COSTS Primary and specialist health care providers and women will be better informed about ovarian aging and the age-related decline in natural fertility and about options for assisted reproductive technology.