Impact of retinal vein occlusion on cardiovascular events in elderly Japanese patients.
Impact of retinal vein occlusion on cardiovascular events in elderly Japanese patients.
复制标题
DOI：
10.1097/md.0000000000028424
复制
发表时间：
2021-12-30
期刊：
影响因子：
1.6
通讯作者：
Ono K
中科院分区：
文献类型：
--
作者：
Umeya R;Yoshida Y;Ono K
评估视网膜静脉阻塞 (RVO) 与心血管 (CV) 事件发生率之间的关系。这是一项单机构回顾性队列研究。我们入组了 2012 年 1 月至 2019 年 12 月期间诊断为 RVO 的 57 名患者，以及 2012 年 1 月至 4 月期间由一位外科医生接受过白内障手术的 125 名非 RVO 患者。我们比较了两组之间 CV 事件的相对风险和发生率比。此外，还进行生存分析，使用 Cox 比例风险模型计算风险比 (HR)。 RVO、年龄、性别、血压、体重指数、是否患有糖尿病、血液样本数据和吸烟被认为是混杂因素。 RVO 组和非 RVO 组的平均观察期（±标准差）分别为 2.68±2.04 年和 2.81±2.70 年。 RVO 组观察到 7 例 CV 事件，非 RVO 组观察到 2 例。相对风险和发病率比分别为 7.68（95% 置信区间 [CI]：1.65-35.8）和 8.07（95% CI：1.54-79.6）。多变量分析显示，RVO 组心血管事件的 HR 较高（HR：16.13 [95% CI：2.29–113.74]）且年龄较高（HR：1.26 [95% CI：1.06–1.49]）。 RVO 可以预测未来的心血管事件，尤其是在老年人群中。眼科医生和内科医生应共享眼底观察结果，以防止未来发生心血管事件。
To assess the relationship between retinal vein occlusion (RVO) and the incidence of cardiovascular (CV) events. This was a single-institution, retrospective cohort study. We enrolled 57 patients diagnosed with RVO between January 2012 and December 2019, and 125 non-RVO patients who had undergone cataract surgery by a single surgeon between January and April 2012. We compared the relative risk and incidence rate ratio of CV events between the 2 groups. In addition, survival analysis was performed to calculate the hazard ratio (HR) using the Cox proportional hazards model. RVO, age, sex, blood pressure, body mass index, presence of diabetes, blood sample data, and smoking were considered confounders. The mean observation period (± standard deviation) for the RVO and non-RVO groups was 2.68 ± 2.04 and 2.81 ± 2.70 years, respectively. Seven CV events were observed in the RVO group and 2 in the non-RVO group. Relative risk and incidence rate ratio were 7.68 (95% confidence interval [CI]: 1.65–35.8) and 8.07 (95% CI: 1.54–79.6), respectively. Multivariate analysis revealed that the RVO group had a high HR for CV events (HR: 16.13 [95% CI: 2.29–113.74]) and older age (HR: 1.26 [95% CI: 1.06–1.49]). RVO can predict future CV events, especially in the elderly population. Fundus observations should be shared between ophthalmologists and internists to prevent future CV events.