Efeitos da adição de montmorilonita sódica na dieta sobre o perfil bioquímico de frangos de corte intoxicados com aflatoxina

Efeitos da adição de montmorilonita sódica na dieta sobre o perfil bioquímico de frangos de corte intoxicados com aflatoxina
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黄曲霉毒素

DOI：
10.1590/s0103-84782005000400012
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发表时间：
2005
期刊：
影响因子：
--
通讯作者：
D. Martins
D. Martins
中科院分区：
--
文献类型：
--
作者：
P. N. Batina;Sonia Terezinha dos Anjos Lopes;Jânio Moraes Santurio;C. Souza;D. Martins

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本研究旨在探讨饲粮中添加钠化蒙脱石对黄曲霉毒素中毒肉鸡肝脏生化指标和肾脏酶活性的影响。选用528只柯布氏’肉鸡，随机分为6个处理（T1）对照：正常饮食;（T2）含5 ppm黄曲霉毒素的饮食;（T3）含0.25%钠蒙脱石的饮食;（T4）含5 ppm黄曲霉毒素+0.25%钠蒙脱石的饮食;（T5）含0.5%钠蒙脱石的饮食;（T6）含5 ppm黄曲霉毒素+0.5%钠蒙脱石的饮食。治疗T2显示尿酸、白蛋白、胆固醇、肌酐、甘油三酯、球蛋白和总血清蛋白水平显著降低，血清丙氨酸氨基转移酶（ALT）活性升高。天冬氨酸氨基转移酶（AST）在治疗间未显示出重要差异。在处理T3和T5中，与处理T1相比，生化值没有变化。在饲料中添加0.5%的蒙脱石（T6），与0.25%的钠质蒙脱石（T4）相比，在增加黄曲霉毒素的吸附方面表现出更好的结果。显然，结果表明，饮食中高水平的黄曲霉毒素（5 ppm）导致肉鸡血清酶活性的重要变化。此外，还证明了使用钠质蒙脱石可用于避免由黄曲霉毒素污染的食物引起的风险。
The aim of this research was to evaluate the hepatic biochemical profile and the renal enzymatic activity of broiler chicken experimentally intoxicated with aflatoxin and supplemented with sodic montmorilonite on the diet. 528 Cobb’s broiler chickens were used divided in 6 treatments (from 1st to the 42th day of life) as described: (T1) control: normal diet; (T2) diet with 5ppm of aflatoxin; (T3) diet with 0.25% sodic montmorilonite; (T4) diet with 5 ppm of aflatoxin + 0.25% sodic montmorilonite; (T5) diet with 0.5% sodic montmorilonite; (T6) diet with 5 ppm of aflatoxin + 0.5% sodic montmorilonite. The treatment T2 showed significantly decreased levels of uric acid, albumin, cholesterol, creatinine, triglycerides, globulins and total serum proteins and an increase of serum alanine aminotransferase (ALT) activity. Aspartate aminotransferase (AST) did not showed important differences among treatments. In treatments T3 and T5, there were no variations on the biochemical values, when compared to treatment T1. Addition of 0.5% of montmorilonite in the diet (T6), presented better results on the increase of the adsorption of aflatoxin when compared to 0.25% sodic montmorilonite (T4). Clearly, the results showed that high levels of aflatoxin in the diet (5ppm) causes important changes in the serum enzymatic activity of broiler chickens. Also, it was demonstrated that using sodic montmorilonite may be used to avoid risks caused by food contaminated by aflatoxins.