Immune functional impacts of oyster peptide-based enteral nutrition formula (OPENF) on mice: a pilot study
Immune functional impacts of oyster peptide-based enteral nutrition formula (OPENF) on mice: a pilot study
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DOI：
10.1007/s00343-013-2311-z
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发表时间：
2013-07-01
影响因子：
--
通讯作者：
Sun Huili
中科院分区：
文献类型：
--
作者：
Cai Bingna;Pan Jianyu;Sun Huili
Oyster peptides were produced from Crassostrea hongkongensis and used as a new protein source for the preparation of an oyster peptide-based enteral nutrition formula (OPENF). Reserpineinduced malabsorption mice and cyclophosphamide-induced immunosuppression mice were used in this study. OPENF powder is light yellow green and has a protein-fat-carbohydrate ratio of 16:9:75 with good solubility in water. A pilot study investigating immune functional impacts of the OPENF on mice show that the OPENF enhanced spleen lymphocyte proliferation and the activity of natural killer (NK) cells in BALB/c mice. Furthermore, OPENF can improve intestinal absorption, increase food utilization ratio, and maintain the normal physiological function of mice. These results suggest that oyster peptides could serve as a new protein source for use in enteral nutrition formula, but more importantly, also indicate that OPENF has an immunostimulating effect in mice.
