A trial for fine and low-dose imaging of biological specimens using quasi-monochromatic laser-Compton X-rays
A trial for fine and low-dose imaging of biological specimens using quasi-monochromatic laser-Compton X-rays
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DOI：
10.1016/j.nima.2009.05.157
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发表时间：
2009-09
影响因子：
1.4
通讯作者：
K. Yamada;R. Kuroda;H. Toyakawa;H. Ikeura-Sekiguchi;M. Yasumoto;M. Koike;F. Sakai;K. Mori;H. Mori;N. Fukuyama;E. Sato
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文献类型：
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作者：
K. Yamada;R. Kuroda;H. Toyakawa;H. Ikeura-Sekiguchi;M. Yasumoto;M. Koike;F. Sakai;K. Mori;H. Mori;N. Fukuyama;E. Sato
通过逆康普顿散射过程产生的激光康普顿X/γ射线被公认为是基础科学和工业技术中的优秀工具。在国家先进工业科学技术研究所（AIST），两个基于紧凑型S波段直线加速器和多功能存储环的康普顿系统正在10- 40 keV和1- 40 MeV的光子能量范围内工作。低能量范围的康普顿X射线由于其部分空间相干性和准单色性而被认为适合于在生物或医学中进行精细和低剂量成像。在这里，我们报告了一些使用相位衬度和K边缘衬度方案的康普顿X射线医学成像的典型示例。它也将表明，一个独特的图像是由一个单一的拍摄皮秒康普顿X射线脉冲，这将使我们不仅采取静态拍摄的动态行为的器官，但也实现了实时运动图像使用连续获得的单次拍摄的图像。
The laser-Compton X/gamma-rays produced through the inverse-Compton scattering process are acknowledged as excellent tools in basic science and industrial technologies. At the National Institute of Advanced Industrial Science and Technology (AIST), two Compton systems based on a compact S-band linac and a versatile storage ring are working in photon energy ranges of 10–40keV and 1–40MeV. Compton X-rays in the lower energy range are thought to be suitable to make the fine and low-dose imaging in biology or medicine due to their partial spatial coherence and quasi-monochromaticity. Here we report some typical examples for medical imaging by Compton X-rays using the phase-contrast and K-edge-contrast schemes. It will be also shown that a distinctive image was taken by a single-shot picosecond Compton X-ray pulse which will enable us not only to take a still-shot of dynamic behaviour in organs but also to achieve a real-time motion picture using successively obtained single-shot images.