Acceptability and feasibility of medical abortion with mifepristone and misoprostol in Nigeria

Acceptability and feasibility of medical abortion with mifepristone and misoprostol in Nigeria
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DOI:
10.1016/j.ijgo.2013.10.009
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发表时间:
2014-04-01
影响因子:
3.8
通讯作者:
Winikoff, Beverly
Winikoff, Beverly
中科院分区:
医学4区
文献类型:
--
作者:
Okonofua, Friday;Shittu, Oladapo;Winikoff, Beverly

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目的:探讨药物流产在尼日利亚的可接受性和可行性。研究方法:2005年5月至2006年10月期间,贝宁市和扎里亚共招募了250名符合法律的终止妊娠条件的妇女,她们的孕龄为末次月经后63天。参与者在诊所接受200毫克口服米非司酮,然后在2天后服用400微克口服米索前列醇-选择返回诊所或在家服用。2周后,妇女返回进行流产状态评估。结果:绝大多数(96.3%)的妇女成功完成了完全流产。超声用于确定不到三分之一(28.9%)的参与者的结果。大多数妇女(83.2%)在家中服用米索前列醇。几乎所有(96.2%)参与者对堕胎方法感到满意或非常满意。结论:在尼日利亚和其他获得法律的堕胎服务有限的环境中,采用米非司酮和米索前列醇药物堕胎可以大大扩大现有方法的选择,提高生殖保健的质量。(C)2014年国际妇产科联合会。由Elsevier爱尔兰有限公司出版。保留所有权利。
Objective: To examine the acceptability and feasibility of medical abortion in Nigeria. Methods: In total, 250 women who were eligible for legal pregnancy termination with a gestational age of up to 63 days since last menstrual period were enrolled in Benin City and Zaria between May 2005 and October 2006. Participants received 200 mg of oral mifepristone in the clinic and then took 400 mu g of oral misoprostol 2 days later-choosing to either return to the clinic or take it at home. Women returned 2 weeks later for an assessment of abortion status. Results: The vast majority (96.3%) of women had successful complete abortions. Ultrasound was used to determine outcome in less than one-third (28.9%) of participants. Most women (83.2%) took the misoprostol at home. Almost all (96.2%) participants were satisfied or very satisfied with the abortion method. Conclusion: The introduction of medical abortion with mifepristone and misoprostol could greatly expand current method options and improve the quality of reproductive health care in Nigeria and other settings in which access to legal abortion services is limited. (C) 2014 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd. All rights reserved.