The effect of fenfluramine on obese, maturity-onset diabetic patients.

The effect of fenfluramine on obese, maturity-onset diabetic patients.
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芬氟拉明对肥胖、成年型糖尿病患者的影响。

DOI:
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发表时间:
1979
期刊:
Acta Endocrinologica
影响因子:
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通讯作者:
J. Wales
J. Wales
中科院分区:
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文献类型:
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作者:
J. Wales

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在一项双盲试验中,对 38 名肥胖的成年型糖尿病患者进行了芬氟拉明治疗对碳水化合物耐受性的影响与安慰剂治疗的比较。芬氟拉明治疗不会影响体重减轻或空腹血糖水平,但对葡萄糖耐量产生轻微但显着的改善。这种改善与体重或胰岛素分泌的任何变化无关。
In 38 obese maturity-onset diabetic patients the effect of fenfluramine therapy on carbohydrate tolerance was compared to placebo therapy in a double blind trial. Fenfluramine therapy did not affect weight loss, or fasting glucose levels but produced a slight but significant improvement in glucose tolerance. This improvement was not correlated with any change in body weight or insulin secretion.