Incidence of New-Onset and Worsening Heart Failure Before and After the COVID-19 Epidemic Lockdown in Denmark A Nationwide Cohort Study
Incidence of New-Onset and Worsening Heart Failure Before and After the COVID-19 Epidemic Lockdown in Denmark A Nationwide Cohort Study
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DOI：
10.1161/circheartfailure.120.007274
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发表时间：
2020-06-01
影响因子：
9.7
通讯作者：
Schou, Morten
中科院分区：
文献类型：
--
作者：
Andersson, Charlotte;Gerds, Thomas;Schou, Morten
背景资料：由于冠状病毒病2019年(新冠肺炎)大流行，丹麦政府于2020年3月12日下令公开封锁。我们调查了这样的封锁对心力衰竭(HF)患者的直接后果。方法：使用丹麦全国行政数据库，我们调查了2020年和2019年封锁前后(1月1日至3月11日与3月12日至3月31日)新发心力衰竭的发生率和因心力衰竭恶化而住院的情况。我们还调查了所有心力衰竭患者和新冠肺炎感染的心力衰竭患者的死亡率。结果：2020年和2019年1月1日至3月11日的新发心力衰竭发生率相似(每万人年1.83人比1.78人；P=0.19)，而因心力衰竭恶化而住院的人数在2020年略高于2019年(每千人年1.04人对0.93人；P=0.02)。在禁闭期内，2020年新发心力衰竭诊断率(1.26‰)和因病情恶化而住院的比率(0.63‰vs 0.99‰)均显著低于2019年(P均
BACKGROUND: The Danish government ordered a public lockdown on March 12, 2020, because of the coronavirus disease 2019 (COVID-19) pandemic. We investigated the immediate consequences of such a lockdown for patients with heart failure (HF).METHODS: Using the Danish nationwide administrative databases, we investigated the incidence of new-onset HF and hospitalizations for worsening HF before and after the lockdown (January 1 to March 11 versus March 12 to March 31) in 2020 versus 2019. We also investigated the mortality for all patients with HF and in COVID-19-infected patients with HF.RESULTS: Rates of new-onset HF between January 1 and March 11 were comparable for 2020 and 2019 (1.83 versus 1.78 per 10 000 person-years; P=0.19), while hospitalizations for worsening HF were slightly higher in 2020 versus 2019 (1.04 versus 0.93 per 1000 person-years; P=0.02). In the lockdown period, rates of new-onset HF diagnoses (1.26 versus 2.25 per 1000 person-years) and of hospitalizations for worsening HF (0.63 versus 0.99 per 1000 person-years) were significantly lower in 2020 versus 2019 (P for both,