High prevalence of irritable bowel syndrome and upper gastrointestinal symptoms in patients with chronic renal failure.
High prevalence of irritable bowel syndrome and upper gastrointestinal symptoms in patients with chronic renal failure.
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发表时间：
2005
影响因子：
3.4
通讯作者：
S. Kahvecioğlu;I. Akdag;M. Kıyıcı;M. Gullulu;M. Yavuz;A. Ersoy;K. Dilek;M. Yurtkuran
中科院分区：
文献类型：
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作者：
S. Kahvecioğlu;I. Akdag;M. Kıyıcı;M. Gullulu;M. Yavuz;A. Ersoy;K. Dilek;M. Yurtkuran
背景慢性肾衰竭患者常见胃肠道症状和精神疾病，因为尿毒症影响所有系统以及胃肠道。肠易激综合征（IBS）是一种常见的功能性疾病。我们的目的是评估IBS和上消化道症状的频率在慢性肾功能衰竭（CRF）患者。在同一患者组中，IBS、性别和其他精神疾病之间的关系被确定，并将结果与对照组进行比较。方法选择93例血液透析（HD）患者和35例腹膜透析（PD）患者及51例健康志愿者为研究对象。他们完成了调查问卷，随后进行了评估，以确定HD，PD和对照组中IBS的频率;这三组中抑郁和焦虑的频率及其与性别的关系。还调查了各组的上消化道症状及其与性别的关系。结果：在这项研究中，我们已经证明，IBS的患病率在慢性肾功能衰竭的血液透析或腹膜透析患者高于对照组，虽然透析类型似乎并不影响IBS患病率本身。上腹痛在HD患者中比PD患者更常见。结论：本研究表明，虽然IBS在CRF患者中很常见，但通常被低估。透析类型似乎并没有太大改变临床情况。伴随的情绪障碍也必须考虑在内。
BACKGROUND Gastrointestinal symptoms and psychiatric disorders are common among patients with chronic renal failure since uremia affects all systems as well as the gastrointestinal tract. Irritable bowel syndrome (IBS) is a frequent functional disorder worldwide. We aimed to evaluate the frequency of IBS and upper gastrointestinal symptoms in patients with chronic renal failure (CRF). The relationships between IBS, sex and additional psychiatric disorders in the same patient group were determined and results were compared with controls. METHODS Ninety-three hemodialysis (HD) and 35 peritoneal dialysis (PD) patients and 51 healthy volunteers were enrolled in this cross-sectional study. They completed the questionnaires that were later evaluated to determine the frequency of IBS in HD, PD and control groups; the frequency of depression and anxiety in these three groups and their relationship to sex. Symptoms of upper gastrointestinal system and their relation to sex were also investigated in all groups. RESULTS In this study, we have demonstrated that prevalence of IBS in patients with chronic renal failure on hemodialysis or peritoneal dialysis is higher than the controls though the type of dialysis does not seem to influence the IBS prevalence itself. Epigastric pain was more prevalent in HD patients than PD patients. CONCLUSIONS The present study suggests that though IBS is common in patients with CRF, it is generally underestimated. Type of dialysis does not seem to change the clinical picture much. Accompanying mood disorders must also be taken into consideration.