Digital thermal monitoring of vascular function: a novel tool to improve cardiovascular risk assessment.
Digital thermal monitoring of vascular function: a novel tool to improve cardiovascular risk assessment.
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DOI：
10.1177/1358863x08098850
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发表时间：
2009-05
期刊：
影响因子：
--
通讯作者：
Naghavi M
中科院分区：
文献类型：
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作者：
Gul KM;Ahmadi N;Wang Z;Jamieson C;Nasir K;Metcalfe R;Hecht HS;Hartley CJ;Naghavi M
袖带闭塞反应性充血期间血管功能的数字热监测（DTM）依赖于缺血刺激期间和之后指尖温度的变化反映血流变化的前提。为了确定DTM在有或没有已知冠心病（CHD）患者中的应用，133名连续患者（年龄54±10岁，50%为男性，19名已知冠心病）在手臂袖带超收缩期膨胀期间和之后2分钟接受了DTM。同时测量闭塞和未闭塞指尖的指尖温度。与正常组相比，冠心病患者和Framingham风险评分（FRS）升高的患者袖带后通缩温度反弹（TR）较低。在校正了年龄、性别和心脏危险因素后，冠心病患者的TR明显低于无冠心病患者（p < 0.05）。本研究表明，DTM测量的血管功能障碍与冠心病和FRS升高有关，可能用于识别高危患者。
Digital thermal monitoring (DTM) of vascular function during cuff-occlusive reactive hyperemia relies on the premise that changes in fingertip temperature during and after an ischemic stimulus reflect changes in blood flow. To determine its utility in individuals with and without known coronary heart disease (CHD), 133 consecutive individuals (age 54 ± 10 years, 50% male, 19 with known CHD) underwent DTM during and after 2 minutes of supra-systolic arm cuff inflation. Fingertip temperatures of the occluded and non-occluded fingertips were measured simultaneously. Post-cuff deflation temperature rebound (TR) was lower in the CHD patients and in those with an increased Framingham risk score (FRS) compared to the normal group. After adjustment for age, sex, and cardiac risk factors, TR was significantly lower in those with CHD compared to those without CHD (p < 0.05). This study demonstrates that vascular dysfunction measured by DTM is associated with CHD and an increased FRS, and could potentially be used to identify high-risk patients.