Muscle and mucous gland size in the major bronchi of patients with chronic bronchitis, asthma, and asthmatic bronchitis.

Muscle and mucous gland size in the major bronchi of patients with chronic bronchitis, asthma, and asthmatic bronchitis.
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慢性支气管炎、哮喘和喘息性支气管炎患者主支气管的肌肉和粘液腺大小。

DOI:
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发表时间:
2015
期刊:
American Review of Respiratory Disease
影响因子:
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通讯作者:
W. Thurlbeck
W. Thurlbeck
中科院分区:
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文献类型:
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作者:
T. Takizawa;W. Thurlbeck

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本文对7例典型慢性支气管炎、4例慢性支气管炎喘息发作(慢性喘息性支气管炎)和3例典型痉挛性哮喘患者的支气管粘膜腺大小和肌量进行了测量。哮喘患者支气管肌有增粗,慢性支气管炎患者无增粗。4例喘息性支气管炎患者中有3例肌肉增加;因此,这些患者可以在形态学上识别,并且可能占支气管炎和异常程度气道阻塞患者的比例。当用Dunnill点计数评估时,哮喘患者的粘液腺大小增加,而用Reid指数评估时则无此现象。
Mucous gland size and the amount of muscle in the bronchi were measured in 7 patients with typical chronic bronchitis, 4 patients with chronic bronchitis and attacks of wheezing (chronic asthmatic bronchitis), and 3 patients with classic spasmodic asthma. The patients with asthma had increased bronchial muscle, but the patients with chronic bronchitis did not. Three of the 4 patients with asthmatic bronchitis had increased muscle; such patients can therefore be recognized morphologically, and might account for a proportion of patients with bronchitis and unusual degrees of airways obstruction. Mucous gland size was increased in asthma when assessed by the Dunnill point count, but not by the Reid index.