Effect of high myopia on glaucoma diagnostic parameters measured with optical coherence tomography
Effect of high myopia on glaucoma diagnostic parameters measured with optical coherence tomography
复制标题
DOI：
10.1111/ceo.12318
复制
发表时间：
2014-11-01
影响因子：
4
通讯作者：
Goldberg, Ivan
中科院分区：
文献类型：
--
作者：
Kita, Yoshiyuki;Kita, Ritsuko;Goldberg, Ivan
研究背景：我们检测了高度近视对常规光谱域光学相干断层扫描参数的影响，并评估了作为一种新的光学相干断层扫描参数的黄斑神经节细胞复合体厚度与黄斑外层视网膜厚度的比率。设计前瞻性横断面研究：受试者60只正常眼和30只高度近视眼(屈光度>-6D)。方法我们使用RTVue-100测量黄斑神经节细胞复合体和乳头周围视网膜神经纤维层厚度、整体损失体积和焦点损失体积，然后计算神经节细胞复合体厚度与黄斑外部视网膜厚度的比率。结果正常眼和高度近视眼的神经节细胞复合体和视网膜神经纤维层厚度、整体丢失体积和焦点丢失体积存在显著差异。新的比率参数在两组之间没有显著差异(55.74%比54.50%)。受试者工作特征曲线下面积为0.775(P
BackgroundWe examined the influence of high myopia on conventional spectral-domain optical coherence tomographic parameters and assessed the macular ganglion cell complex thickness to macular outer retinal thickness ratio as a new optical coherence tomography parameter.DesignProspective cross-sectional study.ParticipantsSixty normal and 30 highly myopic eyes (refractive error more than -6 D).MethodsWe used the RTVue-100 to measure macular ganglion cell complex and circumpapillary retinal nerve fibre layer thickness, global loss volume, and focal loss volume and then calculated the ganglion cell complex thickness to macular outer retinal thickness ratio.Main Outcome MeasuresEach parameter was compared between the two groups. Using the area under receiver operating characteristics curve, the classification abilities of optical coherence tomography parameters were examined in highly myopic eyes.ResultsBetween normal and highly myopic eyes, we found significant differences in ganglion cell complex and retinal nerve fibre layer thickness, global loss volume and focal loss volume. The new ratio parameter was not significantly different between groups (55.74% vs. 54.50%). The area under receiver operating characteristics curve was 0.775 (P