NSP1 is a component of the Myc signaling pathway
NSP1 is a component of the Myc signaling pathway
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DOI：
10.1111/nph.12340
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发表时间：
2013-07-01
期刊：
影响因子：
9.4
通讯作者：
Combier, Jean-Philippe
中科院分区：
文献类型：
--
作者：
Delaux, Pierre-Marc;Becard, Guillaume;Combier, Jean-Philippe
结瘤和丛枝菌根化需要分别通过Nod因子、Myc-LCO和CO激活植物宿主共生程序。参与这些信号的感知和下游信号传导的途径包括共同和不同的成分。在不同的成分中，NSP1（一种 GRAS 转录因子）多年来一直被认为专门参与结瘤。在这里，我们分析了丛枝菌根 (AM) 宿主和非 AM 宿主植物中 NSP1 序列的保守程度，并仔细检查了蒺藜苜蓿 nsp1 突变体响应 Myc-LCO 和被丛枝菌根真菌定植的能力。在 AM 寄主植物中，对 NSP1 的选择压力比非 AM 寄主植物更强。 nsp1 突变体对 Myc-LCO 的反应和菌根定植频率显着降低。我们的结果表明，之前描述的 NSP1 参与 Nod 因子信号通路，也参与 Myc-LCO 信号通路。他们为结瘤和菌根化之间的进化相关性提供了更多证据。
Nodulation and arbuscular mycorrhization require the activation of plant host symbiotic programs by Nod factors, and Myc-LCOs and COs, respectively. The pathways involved in the perception and downstream signaling of these signals include common and distinct components. Among the distinct components, NSP1, a GRAS transcription factor, has been considered for years to be specifically involved in nodulation. Here, we analyzed the degree of conservation of the NSP1 sequence in arbuscular mycorrhizal (AM) host and non-AM host plants and carefully examined the ability of Medicago truncatula nsp1 mutants to respond to Myc-LCOs and to be colonized by an arbuscular mycorrhizal fungus. In AM-host plants, the selection pressure on NSP1 is stronger than in non-AM host ones. The response to Myc-LCOs and the frequency of mycorrhizal colonization are significantly reduced in the nsp1 mutants. Our results reveal that NSP1, previously described for its involvement in the Nod factor signaling pathway, is also involved in the Myc-LCO signaling pathway. They bring additional evidence on the evolutionary relatedness between nodulation and mycorrhization.