Protein structure fitting and refinement guided by cryo-EM density
Protein structure fitting and refinement guided by cryo-EM density
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DOI：
10.1016/j.str.2007.11.016
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发表时间：
2008-02-01
期刊：
影响因子：
5.7
通讯作者：
Sali, Andrej
中科院分区：
文献类型：
--
作者：
Topf, Maya;Lasker, Keren;Sali, Andrej
对于许多大分子组装，冷冻电子显微镜图和其组分蛋白质的原子结构都是可用的。在这里，我们描述了一种方法，用于在其地图中以中间分辨率拟合和细化组件结构（
For many macromolecular assemblies, both a cryo-electron microscopy map and atomic structures of its component proteins are available. Here we describe a method for fitting and refining a component structure within its map at intermediate resolution (