Electrospray ionization Fourier transform ion cyclotron resonance at 9.4 T.
Electrospray ionization Fourier transform ion cyclotron resonance at 9.4 T.
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DOI:
10.1002/(sici)1097-0231(199611)10:14
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发表时间:
1996
期刊:
影响因子:
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通讯作者:
M. Senko;C. Hendrickson;L. Paša-Tolić;J. Marto;F. White;S. Guan;A. G. Marshall
中科院分区:
文献类型:
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作者:
M. Senko;C. Hendrickson;L. Paša-Tolić;J. Marto;F. White;S. Guan;A. G. Marshall
We present the first results from a new electrospray ionization Fourier transform ion cyclotron resonance mass spectrometer operated at a magnetic field of 9.4 T (i.e. > or = 2.4 T higher than for any prior FTICR instrument). The 9.4 T instrument provides substantially improved performance for large molecules (> or = 50% increase in mass resolving power) and complex mixtures (> or = 100% increase in dynamic range) compared to lower-field ( 200,000, routinely for porcine serum albumin (67 kDa). The present performance guides further modifications of the instrument, which should lead to significant further improvements.