Nontyphoidal salmonellosis
Nontyphoidal salmonellosis
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DOI：
10.1086/318457
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发表时间：
2001-01-15
影响因子：
11.8
通讯作者：
Hohmann, EL
中科院分区：
文献类型：
--
作者：
Hohmann, EL
非伤寒沙门氏菌是引起胃肠炎、菌血症和随后的局灶性感染的重要食源性病原体。这些哈代细菌在各种免疫功能低下的个体中尤其成问题，所述免疫功能低下的个体包括（但不限于）患有恶性肿瘤、人类免疫缺陷病毒或糖尿病的患者，以及那些接受皮质类固醇治疗或用其它免疫治疗剂治疗的患者。血管内感染和深部骨或内脏脓肿是重要的并发症，可能难以治疗。感染部位和个体的免疫状态影响治疗选择。非伤寒沙门氏菌对氟喹诺酮类和第三代头孢菌素的耐药性的预兆最近已有报道，这种耐药性可能是未来的治疗问题。目前的报告提出了一个简短的概述的问题和趋势与沙门氏菌感染的临床医生感兴趣的。
Nontyphoidal Salmonella are important foodborne pathogens that cause gastroenteritis, bacteremia, and subsequent focal infection. These hardy bacteria are especially problematic in a wide variety of immunocompromised individuals, including (but not limited to) patients with malignancy, human immunodeficiency virus, or diabetes, and those receiving corticosteroid therapy or treatment with other immunotherapy agents. Endovascular infection and deep bone or visceral abscesses are important complications that may be difficult to treat. The site of infection and the individual's immune status influence treatment choices. The harbingers of resistance of nontyphoidal Salmonella to both fluoroquinolones and third-generation cephalosporins have been reported recently, and such resistance is likely to be a therapeutic problem in the future. The current report presents a brief overview of the problems and trends associated with salmonellosis that are of interest to the infectious diseases clinician.