Traceless Chelation-Controlled Rhodium-Catalyzed Intermolecular Alkene and Alkyne Hydroacylation
Traceless Chelation-Controlled Rhodium-Catalyzed Intermolecular Alkene and Alkyne Hydroacylation
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DOI：
10.1002/chem.201204056
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发表时间：
2013-02-01
影响因子：
4.3
通讯作者：
Willis, Michael C.
中科院分区：
文献类型：
--
作者：
Hooper, Joel F.;Young, Rowan D.;Willis, Michael C.
一种新的官能团耐受，铑催化，硫化物还原过程与铑催化的螯合控制的氢酰化反应相结合，得到一个无痕的氢酰化方案。芳基醛和烯基醛可以与烯烃、炔和联烯结合，以高产率得到无痕产物。并提出了初步的机理建议。
A new functional-group tolerant, rhodium-catalyzed, sulfide-reduction process is combined with rhodium-catalyzed chelation-controlled hydroacylation reactions to give a traceless hydroacylation protocol. Aryl- and alkenyl aldehydes can be combined with both alkenes, alkynes and allenes to give traceless products in high yields. A preliminary mechanistic proposal is also presented.