Contrast-Dependent Variations in the Excitatory Classical Receptive Field and Suppressive Nonclassical Receptive Field of Cat Primary Visual Cortex
Contrast-Dependent Variations in the Excitatory Classical Receptive Field and Suppressive Nonclassical Receptive Field of Cat Primary Visual Cortex
复制标题
猫初级视觉皮层的兴奋性经典感受野和抑制性非经典感受野的对比度相关变化
DOI：
10.1093/cercor/bhs012
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发表时间：
2013-02-01
期刊：
影响因子：
3.7
通讯作者：
Li, Chao-Yi
中科院分区：
文献类型：
--
作者：
Chen, Ke;Song, Xue-Mei;Li, Chao-Yi
在猫和猴的V1区，在经典感受野（CRF）之外有一个环绕区，它本身是无反应的，但可能调节细胞的反应。这个领域被称为“非经典感受野”（nCRF）。已有研究表明，猴V1神经元的CRF和（或）nCRF的程度不是固定的，而是随着刺激对比度的不同而变化。我们重新研究了猫V1神经元的对比度依赖性，以确定这是否与以前在猕猴中的研究不同。通过用差分高斯模型拟合不同对比度下的空间求和曲线，定量估计对比度对CRF和nCRF的空间范围以及周围抑制强度的影响。我们的结果表明，CRF和nCRF在低对比度下都有扩张，但CRF的扩张比nCRF更明显。虽然对比度对环绕抑制的影响各不相同，但在高对比度下，总体抑制显著增加。此外，CRF程度的对比度依赖性变化与抑制强度的变化无关。总的来说，我们在猫的结果是一致的猕猴钱。
In area V1 of cat and monkey, there is a surround region beyond the classical receptive field (CRF) which alone is unresponsive but may modulate the cell's response. This field is referred to as the "nonclassical receptive field" (nCRF). It has been reported in monkey that the extent of CRF and/or nCRF of V1 neurons is not fixed but varies with stimulus contrast. We reexamined the contrast dependence of V1 neurons in cat to determine whether this differs from previous studies in macaque. By fitting the spatial summation curves obtained at different contrasts with a difference of Gaussians model, we estimated quantitatively the effect of contrast on the spatial extent of the CRF and nCRF as well as the strength of surround suppression. Our results showed that both the CRF and nCRF expanded at low contrast, but the expansion is more marked for the CRF than for the nCRF. Although the effect of contrast on surround suppression was varied, the overall suppression increased significantly at high contrast. Moreover, the contrast-dependent change in the extent of CRF is independent of the change in suppression strength. Overall, our results in cat are in agreement with those obtained in macaque money.