Developmentally regulated expression of two members of the Nrarp family in zebrafish
Developmentally regulated expression of two members of the Nrarp family in zebrafish
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DOI：
10.1016/s1567-133x(03)00009-7
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发表时间：
2003-05-01
影响因子：
1.2
通讯作者：
Hogan, BLM
中科院分区：
文献类型：
--
作者：
Topczewska, JM;Topczewski, J;Hogan, BLM
Delta-Notch信号对于脊椎动物胚胎的体细胞发生至关重要。在寻找控制斑马鱼体形成的基因的过程中，我们已经确定了两个编码与nrap （Notch调节的锚蛋白重复蛋白）相关的蛋白质的副同源物。斑马鱼nrap -a和b编码具有两个锚蛋白重复结构域的小蛋白。在这里，我们报告了这两个基因在正常和突变胚胎中的表达模式。(C) 2003 Elsevier Science B.V.版权所有
Delta-Notch signaling is essential for somitogenesis in vertebrate embryos. In a search for genes that control somite formation in zebrafish we have identified two paralogues encoding proteins related to Nrarp (Notch regulated ankyrin repeat protein). Zebrafish nrarp-a and-b encode small proteins with two ankyrin repeat domains. Here, we report the expression patterns of both genes in normal and mutant embryos. (C) 2003 Elsevier Science B.V. All rights reserved.