Treatment options for giant congenital naevi
Treatment options for giant congenital naevi
复制标题
先天性巨大痣的治疗选择
DOI：
10.1046/j.1365-2230.2000.00560.x
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发表时间：
2000
影响因子：
4.1
通讯作者：
Lawrence
中科院分区：
文献类型：
--
作者：
Lawrence
先天性巨痣（GCN）是一种在出生时就存在的毁容、潜在恶性的色素痣。GCN中的痣细胞遍布真皮，有时穿透皮下隔。据称，浅表的、色素更重的和生物学上不同的痣细胞位于真皮上层。通过磨皮术、激光治疗、刮除术或剃刮切除术部分去除这些浅表痣细胞比切除手术创伤小，并且产生可接受的美容效果。然而，这些技术或切除GCN到浅表脂肪都不能完全消除恶性转化的风险。
Giant congenital naevi (GCN) are disfiguring, potentially malignant pigmented naevi present at birth. The naevus cells in GCN are found throughout the dermis and sometimes penetrate the subcutaneous septa. It is claimed that superficial, more heavily pigmented and biologically different naevus cells reside in the upper dermis. Partial removal of these superficial naevus cells by dermabrasion, laser therapy, curettage or shave excision is less traumatic than excision surgery and produces an acceptable cosmetic result. However, none of these techniques or excision of GCN to superficial fat completely removes the risk of malignant transformation.