Synthesis of strigolactones, a strategic account.
Synthesis of strigolactones, a strategic account.
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独脚金内酯的合成，一个战略帐户。
DOI：
10.1002/ps.4229
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发表时间：
2016
影响因子：
4.1
通讯作者：
Tomáš Pospíšil
中科院分区：
文献类型：
--
作者：
B. Zwanenburg;S. Ćavar Zeljković;Tomáš Pospíšil
独脚金内酯（SL）是一类新的植物激素，近年来受到越来越多的关注。它们最初被认为是寄生植物识别宿主的信号分子，以及植物与丛枝菌根真菌共生的信号分子。此外，它们还参与植物的许多生理过程，如植物结构的调节和对非生物因子的响应。SL由植物以极低的量产生，并且它们在纯化过程中可能不稳定。因此，它们的全合成对于根据光谱和其他物理数据确认指定的结构具有高度相关性。SL研究的第二个重要主题是SL类似物的设计和合成，这些类似物具有简化的结构，同时仍然具有基本的生物学特性。本文综述了天然SL的合成策略，以及具有生物活性的SL类似物的设计和合成。
Strigolactones (SLs) constitute a new class of plant hormones that have received growing interest in recent years. They firstly became known as signalling molecules for host recognition by parasitic plants, and for symbiosis of plants with arbuscular mycorrhizal fungi. Furthermore, they are involved in numerous physiological processes in plants, such as the regulation of plant architecture and the response to abiotic factors. SLs are produced by plants in extremely low quantities, and they may be unstable during the purification process. Therefore, their total synthesis is highly relevant for confirming the structures assigned on the basis of spectroscopic and other physical data. A second important theme in SL research is the design and synthesis of SL analogues that have a simplified structure while still featuring the essential bioproperties. This review summarises the strategy and synthesis of naturally occurring SLs, and the design and synthesis of SL analogues with appreciable bioactivity.