Trajectories of Hospitalization in COVID-19 Patients: An Observational Study in France.
Trajectories of Hospitalization in COVID-19 Patients: An Observational Study in France.
复制标题
DOI：
10.3390/jcm9103148
复制
发表时间：
2020-09-29
影响因子：
3.9
通讯作者：
Robineau O
中科院分区：
文献类型：
--
作者：
Boëlle PY;Delory T;Maynadier X;Janssen C;Piarroux R;Pichenot M;Lemaire X;Baclet N;Weyrich P;Melliez H;Meybeck A;Lanoix JP;Robineau O
描述医院中COVID-19患者的特征对于协助未来医院容量的管理具有重要意义。在这里，我们分析了法国北部和东部医院收治的 1321 名患者的轨迹。我们发现，从发病到住院的时间随着年龄的增长而缩短，从 20-65 岁的 7.3 天减少到 >80 岁的 4.5 天（p < 0.0001）。总体住院时间为15.9天，死亡率为20%。四分之一的患者住进重症监护室 (ICU) 大约一个月。轨迹特征随年龄而变化：入住ICU的老年患者较少，老年人死亡率较高。发病后不久入院与死亡率增加（比值比 (OR) = 1.8，置信区间 (CI) 95% [1.3, 2.6]）以及男性（OR = 2.1，CI 95% [1.5, 2.9]）相关。从入院到转入ICU的时间很短。在流行病过程中，年龄和性别调整后的死亡率有所下降，这表明护理随着时间的推移而有所改善。在SARS-CoV-2疫情中，入院时对ICU的迫切需求以及ICU住院时间的延长对床位管理和护理组织提出了挑战。
Describing the characteristics of COVID-19 patients in the hospital is of importance to assist in the management of hospital capacity in the future. Here, we analyze the trajectories of 1321 patients admitted to hospitals in northern and eastern France. We found that the time from onset to hospitalization decreased with age, from 7.3 days in the 20–65 year-olds to 4.5 in the >80 year-olds (p < 0.0001). Overall, the length of stay in the hospital was 15.9 days, and the death rate was 20%. One patient out of four was admitted to the intensive care unit (ICU) for approximately one month. The characteristics of trajectories changed with age: fewer older patients were admitted to the ICU and the death rate was larger in the elderly. Admission shortly after onset was associated with increased mortality (odds-ratio (OR) = 1.8, Confidence Interval (CI) 95% [1.3, 2.6]) as well as male sex (OR = 2.1, CI 95% [1.5, 2.9]). Time from admission within the hospital to the transfer to ICU was short. The age- and sex-adjusted mortality rate decreased over the course of the epidemic, suggesting improvement in care over time. In the SARS-CoV-2 epidemic, the urgent need for ICU at admission and the prolonged length of stay in ICU are a challenge for bed management and organization of care.
登录
查看更多内容
影响因子：
120.7
作者：
Cavalcanti, Alexandre Biasi;Suzumura, Erica Aranha;Ribeiro de Carvalho, Carlos Roberto
通讯作者：
Ribeiro de Carvalho, Carlos Roberto
影响因子：
11.1
作者：
Imam, Z.;Odish, F.;Halalau, A.
通讯作者：
Halalau, A.
影响因子：
4.1
作者：
Flaatten, Hans;Van Heerden, Vernon;DeLange, Dylan W.
通讯作者：
DeLange, Dylan W.
影响因子：
39
作者：
Gupta, Shruti;Hayek, Salim S.;Leaf, David E.
通讯作者：
Leaf, David E.
DOI：
10.1164/ajrccm.156.6.9702005
发表时间：
1997-12-01
影响因子：
24.7
作者：
Riquelme, R;Torres, A;Soler, N
通讯作者：
Soler, N