Identification and characterization of MARCKS in Xenopus laevis
Identification and characterization of MARCKS in Xenopus laevis
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DOI：
10.1006/bbrc.1997.6604
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发表时间：
1997-05-08
影响因子：
3.1
通讯作者：
Hayslett, JP
中科院分区：
文献类型：
--
作者：
Ali, N;Macala, LJ;Hayslett, JP
MARCKS 蛋白广泛分布于哺乳动物细胞中，并且在信号转导过程检查中作为探针发挥着重要作用，因为它们是激活蛋白激酶 C 的特异性内源性磷酸受体。使用来自非洲爪蟾的培养肾上皮细胞 (A6) 作为实验模型，进行实验以确定 MARCKS 蛋白是否存在于两栖动物中，并显示其作为刺激 PKC 激活底物的有用性。 (C) 1997 年学术出版社。
MARCKS proteins are widely distributed in mammalian cells and subserve an important role as probes in the examination of signal transduction processes because they are specific endogenous phosphoreceptors for activated protein kinase C. Experiments were performed to determine whether MARCKS proteins are present in amphibia and to show their usefulness as substrates for stimulated PKC activation, using cultured renal epithelial cells (A6) derived from Xenopus laevis as an experimental model. (C) 1997 Academic Press.