Growing Awareness: Limited Testing and Screening Bias for Hepatitis Delta Virus in Utah 2000-2021.
Growing Awareness: Limited Testing and Screening Bias for Hepatitis Delta Virus in Utah 2000-2021.
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意识不断增强：2000-2021 年犹他州丁型肝炎病毒检测和筛查偏差有限。
DOI：
10.1093/infdis/jiae023
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发表时间：
2024
期刊：
影响因子：
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通讯作者：
Weller,MelodieL
中科院分区：
文献类型：
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作者：
Hesterman,MatthewC;Fallon,BradenS;Lynch,KeisaM;Weller,MelodieL
本研究评估了2000-2021年间丁型肝炎病毒(HDV)在犹他大学卫生保健系统中的流行情况。方法对HDV/乙肝病毒检测、诊断编码、肝酶和合并症进行分析。结果1962例乙肝患者中，只有22.2%的人进行了HDV检测，HDV合并感染的阳性率为8.3%。这项研究观察到，乙肝和HDV病例持续增加，随着检测的增加，HDV的检测率更高。有限的HDV检测和潜在的筛查偏差是显而易见的。讨论改进的HDV检测和监测对于早期发现和实施靶向治疗至关重要。
BackgroundThis study assessed the epidemiology of hepatitis delta virus (HDV) within the University of Utah UHealth health care system (2000–2021).MethodsAnalysis of HDV/HBV testing, diagnostic codes, liver enzymes, and comorbidities was performed.ResultsAmong the 1962 HBV patients, only 22.2% underwent HDV testing, revealing an 8.3% positivity rate for HDV coinfections. This study observed a consistent increase in HBV and HDV cases, with higher HDV detection rates linked to increased testing. Limited HDV testing and potential screening biases were evident.DiscussionImproved HDV testing and surveillance are crucial for early detection and implementation of targeted therapies.