Preparation of stable dispersion of barium titanate nanoparticles: Potential applications in biomedicine
Preparation of stable dispersion of barium titanate nanoparticles: Potential applications in biomedicine
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DOI：
10.1016/j.colsurfb.2009.12.015
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发表时间：
2010-04-01
影响因子：
5.8
通讯作者：
Menciassi, A.
中科院分区：
文献类型：
--
作者：
Ciofani, G.;Danti, S.;Menciassi, A.
纳米结构和材料由于其独特的性质在生物学领域有着广泛的应用。在这里，我们提出了一个与钛酸钡纳米粒子，一个有趣的陶瓷材料，已经收到了很多的兴趣在纳米技术研究，但没有任何关注其生物学潜力的细胞相互作用的研究。本文首次介绍了一种制备稳定钛酸钡纳米粒子水分散液的有效方法，并通过FIB、TEM和AFM成像、光散射、Z-电位和UV/维斯分析对其进行了表征。最后，我们提出了一个系统的研究短期细胞毒性的制备分散体的基础上定量（代谢，增殖）和定性（细胞凋亡，活力，分化）测定。(C)2009 Elsevier B. V.保留所有权利。
Nanoscale Structures and Materials have been explored in many biological applications because of their extraordinary novel properties. Here we propose a Study of cellular interactions with barium titanate nanoparticles, an interesting ceramic material that has received a lot of interest in the nanotechnology research, but without any attention about its biological potential. We introduced for the first time an efficient method for the preparation of stable aqueous dispersions of barium titanate nanoparticles, characterized with FIB, TEM and AFM imaging, light scattering, Z-potential and UV/vis analysis. Finally, we presented a systematic study Of Short-term cytotoxicity of the prepared dispersion based both on quantitative (metabolism, proliferation) and qualitative (apoptosis, viability, differentiation) assays. (C) 2009 Elsevier B.V. All rights reserved.