Neuroimaging in Mild Traumatic Brain Injury
Neuroimaging in Mild Traumatic Brain Injury
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DOI：
10.1007/s12207-010-9064-1
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发表时间：
2010-03-01
影响因子：
3.1
通讯作者：
Bigler, Erin D.
中科院分区：
文献类型：
--
作者：
Bigler, Erin D.
本文综述了轻度创伤性脑损伤（mTBI）的神经影像学表现。虽然计算机断层扫描仍然是mTBI神经成像的急性标准，但它仅对大体异常敏感，通常作为排除更严重和危及生命的损伤的措施进行。磁共振成像（MRI），特别是在3.0 T的场强下，是评估潜在的潜在脑结构损伤的后续神经影像学标准。几种MRI序列对轻微出血性病变和白色物质中的信号异常特别敏感，当存在于mTBI中时，其灵敏度足以检测病理。沿着讨论了神经心理学结果与神经影像学结果的临床相关性，以及未来功能性神经影像学在评估mTBI患者中的潜力。
Neuroimaging in mild traumatic brain injury (mTBI) is reviewed. While computed tomography remains the acute standard for neuroimaging of mTBI, it is only sensitive to gross abnormalities and is typically performed as a measure to rule out more serious and life-threatening injury. Magnetic resonance imaging (MRI), especially at field strength of 3.0 T, is the follow-up neuroimaging standard for assessing potential underlying structural injury to the brain. Several MRI sequences are particularly sensitive to subtle hemorrhagic lesions and signal abnormalities in white matter, sensitive enough to detect pathology when present in mTBI. Clinical correlation of neuropsychological outcome with neuroimaging findings is discussed along with the future potential for functional neuroimaging in evaluating the mTBI patient.