Fetal microchimerism and cancer.
Fetal microchimerism and cancer.
复制标题
胎儿微嵌合现象和癌症。
DOI：
10.1158/0008-5472.can-08-3008
复制
发表时间：
2008
期刊：
影响因子：
11.2
通讯作者：
Sawicki,JanetA
中科院分区：
文献类型：
--
作者：
Sawicki,JanetA
具有多谱系潜能的胎儿干细胞在怀孕妇女中的持续存在，这种现象被称为胎儿微嵌合体，正在成为某些疾病（包括癌症）的潜在促成因素。例如，胎儿微嵌合体与自身免疫性疾病、伤口愈合和癌症有关。对这一现象的研究可能会为女性癌症提供一个新的视角，包括乳腺癌、卵巢癌和肺癌。[Cancer Res 2008; 68（23）：9567 - 9]
The persistence of fetal stem cells with multilineage potential in women who have been pregnant, a phenomenon known as fetal microchimerism, is emerging as a potential contributing factor in certain diseases, including cancer. For example, fetal microchimerism has been implicated in autoimmune disease, wound healing, and cancer. Studies of this phenomenon may provide a novel perspective on cancer in women, including in breast, ovarian, and lung cancers. [Cancer Res 2008;68(23):9567–9]