Comparison of tissue oximeters on a liquid phantom with adjustable optical properties

Comparison of tissue oximeters on a liquid phantom with adjustable optical properties
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DOI:
10.1364/boe.7.002973
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发表时间:
2016-08-01
影响因子:
3.4
通讯作者:
Wolf, M.
Wolf, M.
中科院分区:
医学2区
文献类型:
--
作者:
Kleiser, S.;Nasseri, N.;Wolf, M.

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SafeBoosC试验表明,脑血氧测定结合治疗指南可将新生儿缺氧负担降低50% [Brit. Med. J. 350,g7635(2015)]。然而,基于一个血氧计的血氧测定的指南不能直接用于其他血氧计。我们制作了一个模拟新生儿头部的血脂模型,以确定不同血氧仪获得的氧合值之间的关系。我们计算了系数,便于从一种血氧计转换到另一种血氧计。我们还确定了相应的SafeBoosC干预阈值,当血红蛋白含量从25 μ M到70 μ M变化时,我们测量的不确定性高达9.2%。总之,本文使不同血氧计获得的绝对值的比较成为可能。(C)2016美国光学学会
The SafeBoosC trial showed that cerebral oximetry combined with a treatment guideline can reduce the the burden of hypoxia in neonates by 50% [Brit. Med. J. 350, g7635 (2015)]. However, guidelines based on oximetry by one oximeter are not directly usable by other oximeters. We made a blood-lipid phantom simulating the neonatal head to determine the relation between oxygenation values obtained by different oximeters. We calculated coefficients for easy conversion from one oximeter to the other. We additionally determined the corresponding SafeBoosC intervention thresholds at which we measured an uncertainty of up to 9.2% when varying hemoglobin content from 25 mu M to 70 mu M. In conclusion, this paper makes the comparison of absolute values obtained by different oximeters possible. (C) 2016 Optical Society of America