Tonic-clonic convulsions in meadow voles.
Tonic-clonic convulsions in meadow voles.
复制标题
草甸田鼠的强直阵挛性惊厥。
DOI：
10.1016/0031-9384(94)90227-5
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发表时间：
1994
影响因子：
2.9
通讯作者：
delaRosa,J
中科院分区：
文献类型：
--
作者：
Bronson,FH;delaRosa,J
一些草甸田鼠(Microtus Pennsylvanicus)在接触或暴露在陌生环境中时，会表现出长时间的强直-阵挛抽搐，可能是癫痫样发作。在这些抽搐之前，通常会有一段时间的缓慢摇头和/或腿部僵硬的跳跃，但从来没有一些哺乳动物抽搐的特征--疯狂的奔跑。草甸田鼠偶尔会因为轻微的干扰而抽搐，就像把家中笼子里的个体从一个房间抬到另一个房间一样。相比之下，它们不能被其他哺乳动物用来诱发癫痫样发作的一些听觉或嗅觉侮辱所诱发。繁殖实验已经确定了草甸田鼠惊厥的遗传基础，这里特别有趣的是，一些抽搐的田鼠是在野外捕获的。这提出了一种有趣的可能性，即自然栖息地的野生田鼠在受到惊吓时可能会容易抽搐。
Some meadow voles (Microtus pennsylvanicus) exhibit prolonged tonic-clonic convulsions, possibly epileptiform seizures, when handled or exposed to a strange environment. These convulsions are often preceded by a period of slow head shaking and/or stifflegged hopping, but never by the explosively wild running bouts that characterize convulsions in some mammals. Convulsions occasionally occur in meadow voles in response to mild disturbance, as when an individual in its home cage is carried from one room to another. In contrast, they can not be elicited by some of the auditory or olfactory insults used to induce epileptiform seizures in other mammals. Breeding experiments have established the genetic basis of the convulsions seen in meadow voles, and of particular interest here is the fact that some of the convulsing voles were caught in the wild. This raises the interesting possibility that wild voles in natural habitats might be susceptible to convulsions when startled.